This case report describes the minimally invasive implantation of a three-component hydraulic penile prosthesis via an infrapubic approach in a 58-year-old male patient with severe Peyronie’s Disease (PD). The procedure was performed at the Department of Urology and Andrology, Sapienza University of Rome, under the supervision of Dr. Paul Perito and Dr. Gabriele Antonini.
The patient had a complex medical history, including arterial hypertension, diabetes mellitus, and chronic erectile dysfunction unresponsive to phosphodiesterase inhibitors (PDE5i) but showing good response to prostaglandin E1 (PGE I). Preoperative evaluation revealed extensive fibrotic involvement and a mid-penile plaque measuring 2.5 x 0.5 cm.
The procedure aimed to correct the dorsal-lateral curvature exceeding 90° using Paul Perito’s innovative “scratch technique,” which ensures optimal cavernous body preparation while minimizing postoperative complications. The infrapubic approach further reduced infection risks and tissue damage, enhancing both the functional and aesthetic outcomes.
The patient underwent a short hospital stay with close monitoring during the first 24 hours. One month postoperatively, the prosthesis was confirmed fully functional, with a marked improvement in sexual quality of life and complete resolution of the pathological curvature.
